ABSTRACT
This article presents the results of the research performed in "1st City Clinic Hospital” (Minsk, Belarus), that included 314 pregnant women with gestational age of 22 weeks and over who underwent screening for anxiety symptoms using PASS-R scale. Two groups were formed according to anxiety symptoms severity: Group 1 (n=47) – women with moderately elevated risk of perinatal anxiety according to PASS-R scale;Group 2 (n=44) – pregnant women with minimally low risk of perinatal anxiety. The results of the research showed that several factors have a statistically significant contribution to the risk of perinatal anxiety development, such as hypertensive disorders in pregnancy (OR 4.686;95% CI 1.223–17.952);threatened miscarriage in the 1st trimester (OR 3.915;95% CI 1.450–10.574);infertility and/or miscarriage episodes in previous pregnancies (OR 4.420;95% CI 1.464–13.344);pregnancy after assisted reproductive technologies (OR 7.525;95% CI 0.886–63.901);negative attitude towards vaccination against COVID-19 (OR 3.771;95% CI 0.949–14.991), and being primiparous (OR 5.167;95% CI 2.107–12.667). © 2022, Professionalnye Izdaniya. All rights reserved.
ABSTRACT
This article presents the results of the research performed in "Center of Reproductive Medicine" (Minsk, Belarus), which included 97 women with infertility that underwent in-vitro fertilization programs. Two groups were formed: Group 1 (n=49) - women that underwent IVF after full course of vaccination against COVID-19 with vector vaccine Gam- COVID-Vac;Group 2 (n=48) - women that underwent IVF without prior vaccination against COVID-19 and without prior confirmed COVID-19 infection. According to the results of the research, vaccination against COVID-19 with vector vaccine Gam-COVID-Vac has no negative impact on controlled ovarian stimulation duration, total gonadotropin dose, and such embryological criteria of efficacy as total quantity of aspirated follicles, mature oocytes, and blastocysts. No negative influence of vaccination on pregnancy rate was revealed: 49% vs 45.8% (χ2=0.096;p=0.757), while vaccination demonstrated statistically significant decrease in the rate of IVF cancellation rates (χ2=7.702;p=0.006), decrease in rates of COVID-19 infection in period after embryo transfer (2.04% vs 36.6%;χ2=18.223;p<0.001). Also, vaccination prior to IVF cycles was associated with significant decrease in reproductive losses in 1st and 2nd pregnancy trimesters: 8.3% vs 31.8% (χ2=4.023;p=0.045). © 2022, Professionalnye Izdaniya. All rights reserved.
ABSTRACT
This article presents the analysis of COVID-19 pandemic impact on European clinics specialized in assisted reproductive technologies;describes the influence of ART partial or complete suspension on patients’ psychological well-being;illustrates leading world scientists’ recommendations on safe ART practices during COVID-19 pandemic, and lists the most sensitive groups of infertile patients that will benefit from timely and prioritized medical assistance in regard to infertility treatment. © 2021, Professionalnye Izdaniya. All rights reserved.